Endocrine Abstracts

Congenital adrenal hyperplasia (CAH) is defined as several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands. Fertility in women with CAH is essential and underestimated clinical problem. According to current studies patients with classic form of CAH due to 21-hydroxylase deficiency have lower fertility rate that c...

Introduction: Recent data showed that PCOS is related to abnormal calcium and phosphate metabolism. The patients are characterized by elevated levels of PTH and decreased levels of vitamin D. Abnormalities in mineral homeostasis are related to insulin resistance. In this study, we assessed a complex of calcium and phosphate metabolism indices in patients diagnosed with PCOS.Material and methods: 60 women, aged 25±5 years diagnosed with PCOS accordin...